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Reports and Findings

Boosting airway T-regulatory cells by gastrointestinal stimulation as a strategy for asthma control

The hallmark of atopic asthma is transient airways hyperresponsiveness (AHR) preceded by aeroallergen-induced Th-cell activation.

Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function

Pulmonary function measures reflect respiratory health and are used in the diagnosis of chronic obstructive pulmonary disease.

Randomised controlled trials in cystic fibrosis: What, when and how?

The major morbidity and mortality from cystic fibrosis (CF) comes from progressive lung disease with bronchiectasis leading to respiratory failure

Environmental Factors in Children's Asthma and Respiratory Effects

Childhood asthma is a condition characterized by airflow obstruction that varies in time spontaneously, in response to various environmental stimuli...

The hygiene hypothesis revisited: role of materno-fetal interactions

For 20 years, the hygiene hypothesis has dominated attempts to explain the increasing prevalence of allergic disease. A causal link between maternal innate immu

Does genetic regulation of IgE begin in utero?

Elucidation of early life factors is critical to understand the development of allergic diseases, especially those manifesting in early life such as food allerg

Th2-associated immunity to bacteria in asthma in teenagers and susceptibility to asthma

Bacterial colonisation of the airways is associated with increased risk of childhood asthma

Risk assessment for respiratory complications in paediatric anaesthesia: a prospective cohort study

Perioperative respiratory adverse events in children are one of the major causes of morbidity and mortality during paediatric anaesthesia.

Deep inspiration and airway physiology: human, canine, porcine, or bovine?

Deep inspiration and airway physiology: human, canine, porcine, or bovine?

Stability of interleukin 8 and neutrophil elastase in bronchoalveolar lavage fluid following long-term storage

Interleukin-8 (IL-8) and neutrophil elastase (NE) are commonly measured markers of inflammation in bronchoalveolar lavage (BAL) fluid from patients with cystic