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Research

Pneumococcal conjugate vaccines PREVenar13 and SynflorIX in sequence or alone in high-risk indigenous infants (PREV-IX-COMBO)

Otitis media (OM) starts within weeks of birth in almost all Indigenous infants living in remote areas of the Northern Territory (NT).

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Antibiotic duration and timing of the switch from intravenous to oral route for bacterial infections in children: systematic review and guidelines

Systematic review of antibiotic duration and timing of intravenous to oral switch for paediatric infectious diseases and evidence-graded recommendations

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Evolution, Evidence and Effect of Secondary Prophylaxis Against Rheumatic Fever

The association between group A streptococcal infection and rheumatic fever (RF) was established in the early 20th century.

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Short-course oral co-trimoxazole versus intramuscular benzathine benzylpenicillin for impetigo in a highly endemic region

The major burden of disease is in developing and tropical settings where topical antibiotics are impractical and lead to rapid emergence of antimicrobial...

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Utility of auscultatory screening for detecting rheumatic heart disease in high-risk children in Australia's Northern Territory

Sensitivity and positive predictive value of cardiac auscultation compared with echocardiography is poor, regardless of the expertise of the auscultator.

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Changes in the clinical and epidemiological features of group A streptococcal bacteraemia in Australia's northern territory

We aimed to measure the incidence and severity of invasive Group A Strep disease in the NT since 1996.

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Effectiveness of clindamycin and intravenous immunoglobulin, and risk of disease in contacts, in invasive group a streptococcal infections

This paper reports on treatment, and preventing infection in close contact, of invasive group A streptococcal (iGAS) using the antibiotic clindamycin and...

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Lessons learned in genetic research with Indigenous Australian participants

We reflect on the lessons learned from a recent genome‐wide association study of rheumatic heart disease with Aboriginal Australian participants

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Reference exome data for Australian Aboriginal populations to support health-based research

Our data set provides a useful reference point for genomic studies on Aboriginal Australians