The way the immune system operates differs between males and females. This is due to both differential expression of immune-related genes from the se…
Respiratory syncytial virus contributes to significant global infant morbidity and mortality. We applied a previously developed statistical predictio…
Neutrophils are the most abundant immune cell in circulation. However, due to a number of technical challenges for researchers, including the neutrop…
Asthma exacerbations in children are associated with respiratory viral infection and atopy, resulting in systemic immune activation and infiltration…
A significant number of babies present transiently with low protein kinase C zeta (PKCζ) levels in cord blood T cells, associated with reduced abilit…
To assess the pharmacokinetics, safety, and tolerability of two high-dose, short-course primaquine (PQ) regimens compared with standard care in child…
Sickle cell disease (SCD) is an inherited red blood cell disease that results in a multitude of medical complications, including an increased risk of…
Because of its beneficial off-target effects against non-mycobacterial infectious diseases, bacillus Calmette-Guérin vaccination might be an accessib…
In 2014, germline signal transducer and activator of transcription (STAT) 3 gain-of-function (GOF) mutations were first described to cause a novel mu…