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Research

A Pre-Clinical Assessment of the Pan-ERBB Inhibitor Dacomitinib in Pediatric and Adult Brain Tumors

Glioblastoma in adults, and medulloblastoma and pineoblastoma that mainly affect children, are aggressive brain tumors.

Research

Record linkage study of the pathogen-specific burden of respiratory viruses in children

Reliance on hospital discharge diagnosis codes alone will likely underestimate the burden of respiratory viruses

Research

The rationale for action to end new cases of rheumatic heart disease in Australia

The choice of RHD is telling: the disease is a marker of inequality, a novel lens for considering health systems and a feasible target for disease control.

Research

Comparative analyses of whole genome sequences of Leishmania infantum isolates from humans and dogs in northeastern Brazil

Overall the analyses do not suggest individual sequence variants account for differences in clinical outcome or adaptation to different hosts.

Research

Viral etiology and the impact of codetection in young children presenting with influenza-like illness

Children with acute respiratory tract infection (ARTI) frequently exhibit virus-virus codetection, yet the clinical significance of ARTI remains contentious.

Research

Extreme heat threatens the health of Australians

Heatwaves have serious health impacts and we need a better approach to prevention and management

Research

Hospital use in Aboriginal and non-Aboriginal patients with chronic disease

Aboriginal people use health services in a different manner when compared to non-Aboriginal people

Research

Motor abnormalities in Rett Syndrome

For most individuals, there is initial developmental progress followed by regression at around 6–30 months. The classic signs of RTT then become apparent.

Research

Differences in serum zinc levels in acutely ill and remitted adolescents and young adults with bulimia nervosa in comparison with healthy controls – a cross-sectional pilot study

Research has implicated that changes in Zn metabolism may be associated with the biological underpinnings of eating disorders, in particular anorexia nervosa.

Research

Behavior in Children with Fetal Alcohol Spectrum Disorders in Remote Australia: A Population-Based Study

Children with FASD have more teacher-reported behavioral impairment than children without FASD. In remote Australian communities, academic performance is poor.