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Research
Malt1 deficient mice develop osteoporosis independent of osteoclast-intrinsic effects of Malt1 deficiencyMalt1 deficient mice develop an osteoporotic phenotype with increased osteoclastogenesis in vivo, but suggest that this is caused by inflammation
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Coffee and tea consumption during pregnancy and risk of childhood acute myeloid leukemia: A Childhood Leukemia International Consortium (CLIC) studyWe investigated the potential association of maternal coffee and tea consumption during pregnancy with childhood acute myeloid leukemia risk
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Primary prevention of severe lower respiratory illnesses in at-risk infants using the immunomodulator OM-85The effects of OM-85 were strongest in the first winter season, with a trend for fewer children in the OM-85 group to have sLRIs and URIs
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The pervasive effects of timing of parental mental health disorders on adolescent deliberate self-harm riskThis study shows that timing is important for understanding intergenerational transmission of deliberate self-harm risk
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RD-RAP: Beyond rare disease patient registries, devising a comprehensive data and analytic frameworkWe introduce and describe the concept of a Rare Disease Registry and Analytics Platform
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No detectable effects of acute tryptophan depletion on short-term immune system cytokine levels in healthy adultsThe acute tryptophan depletion condition did not result in significant changes to cytokine concentrations for the entire study sample
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A population health approach in education to support children's early development: A Critical Interpretive SynthesisThe results from this review indicate that it would indeed be plausible to adapt the population health approach to sites and schools
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Developmental vulnerabilities in children of chronically ill parents: A population-based linked data studyMaternal chronic illness is associated with an increased risk of poor developmental outcomes for children, particularly daughters
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Evaluation of a phased pneumococcal conjugate vaccine introduction in Mongolia using enhanced pneumonia surveillance and community carriage surveysStreptococcus pneumoniae causes substantial morbidity and mortality among children. The introduction of pneumococcal conjugate vaccines (PCV) has the potential to dramatically reduce disease burden. As with any vaccine, it is important to evaluate PCV impact, to help guide decision-making and resource-allocation.
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Mental wellbeing in non-ambulant youth with neuromuscular disorders: What makes the difference?Mental wellbeing was independently associated with academic achievement and perceived family support but not with physical health variables