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The importance of environment on respiratory genotype/phenotype relationships in the InuitThis study aimed to investigate the effects of different macro-environments on asthma genotype-phenotype associations in 2 geographically separated populations
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Boosting airway T-regulatory cells by gastrointestinal stimulation as a strategy for asthma controlThe hallmark of atopic asthma is transient airways hyperresponsiveness (AHR) preceded by aeroallergen-induced Th-cell activation.
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Vitamin D and atopy and asthma phenotypes in children: a longitudinal cohort studyVitamin D has been linked in some studies with atopy- and asthma-associated phenotypes in children with established disease,but its role in disease inception...
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Toll-like receptor 7 function is reduced in adolescents with asthmaAnti-viral innate immune responses may be impaired in asthma, although the mechanisms are not well understood.
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Defective function at the epithelial junction: A novel therapeutic frontier in asthma?The airway epithelium forms a highly regulated physical barrier that normally prevents invasion of inhaled pathogens and allergens from the airway lumen.
News & Events
Asthma steroid without side effectsWestern Australia has joined a major international study that could significantly change the treatment of asthma in children.
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Lung problems continue into childhood for premmie babiesNew research from Perth’s The Kids Research Institute Australia shows that babies born premature continue to have lung problems well into childhood.
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Pharmacological ablation of the airway smooth muscle layer—Mathematical predictions of functional improvement in asthmaFindings provide further proof of concept that pharmacological targeting of airway smooth muscle thickness will be beneficial and may be facilitated by azithromycin
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Could home-based FeNO measurements breathe new life into asthma management?Developing a FeNO test that is affordable enough to allow daily measurements, patients will be able to access quantifiable data to assist them to monitor their asthma
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Systems biology and big data in asthma and allergy: recent discoveries and emerging challengesWe describe recent "omic"-level findings, and examine how these findings have been systematically integrated to generate further insight