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Research
Clindamycin adjunctive therapy for severe Staphylococcus aureus treatment evaluation (CASSETTE)-an open-labelled pilot randomized controlled trialCombination antibiotic therapy with an antitoxin agent, such as clindamycin, is included in some guidelines for severe, toxin-mediated Staphylococcus aureus infections. The evidence to support this practice is currently limited to in vitro, animal and observational human case-series data, with no previous randomized controlled trials (RCTs).
Research
ASCOT ADAPT study of COVID-19 therapeutics in hospitalised patients: an international multicentre adaptive platform trialSARS-CoV-2 infection is associated with a significant risk of hospitalisation, death, and prolonged impact on quality of life. Evaluation of new treatment options and optimising therapeutic management of people hospitalised with SARS-CoV-2 infection remains essential, but rapid changes in pandemic conditions and potential therapies have limited the utility of traditional approaches to randomised controlled trials.
Affecting approximately 400 people in Australia, Rett syndrome is a rare neurological disorder that occurs almost exclusively in girls and affects mobility and development, impacting everything from walking and talking to eating and breathing.
Research
Reflections and perceptions of chronic tinnitus during childhoodReflections and perceptions of chronic tinnitus during childhood
Research
Technical standards for respiratory oscillometryThe aim of the task force was to provide technical recommendations regarding oscillometry measurement
Research
Diffuse Intrinsic Pontine GliomaThis chapter summarizes recent advances in diffuse intrinsic pontine glioma and potential novel therapies
Research
Medulloblastoma therapy generates risk of a poorly-prognostic H3 wild-type subgroup of diffuse intrinsic pontine glioma: a report from the International DIPG RegistryThese findings provide a compelling argument for efforts to reduce exposure of the brainstem in the treatment of medulloblastoma
News & Events
Opinion: Modelling for the health of our next generationNearly 170 years ago a British doctor applied geospatial mapping to identify the source of a cholera outbreak in central London. Using a street map to plot the location of the homes of the sick, Dr John Snow was able to pinpoint a ‘ground zero’ for the outbreak – a contaminated water pump.
News & Events
Government grants to support valuable new child health researchEight The Kids Research Institute Australia-led projects will benefit from the latest round of WA Child Research Fund (WACRF) grants, announced this week by Medical Research Minister Stephen Dawson.
News & Events
New study shows fetal head size could link to autismResearch has found a link between children with larger head measurements in-utero and a subsequent diagnosis of Autism Spectrum Disorder (ASD) as toddlers.