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Research

Exploring change in the Australian version of the Early Development Instrument

Calculating a critical difference for the percentage of children who are “at risk” and “on track” in addition to the children who are developmentally “vulnerable”

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Lao PDR. Early childhood education project Snapshot one: project background and baseline data demographics

This snapshot describes demographic information of the 7,520 children in the baseline sample, including where and how they live.

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What factors contribute to positive early childhood health and development in Australian Aboriginal children? Protocol for a population-based cohort study

Empirical evidence identifying the key drivers of positive early childhood development in Aboriginal children, and supportive features of local communities...

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The impact of maternal gestational stress on motor development in late childhood and adolescence: A longitudinal study

The purpose of this article is to investigate whether the number and timing of stressors experienced during pregnancy impacted longterm motor development at...

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Investigation of the Cross-National Equivalence of a Measurement of Early Child Development

This research paper reports on the results of investigating measurement invariance of the Early Development Instrument (EDI) in two South-Asian countries.

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Subgroups of Temperament Associated with Social-Emotional Difficulties in Infants with Early Signs of Autism

Links between temperament and social-emotional difficulties are well-established in normative child development but remain poorly characterized in autism. We sought to characterize distinct temperament subgroups and their associations with concurrent internalizing and externalizing symptoms in a sample of 103 infants showing early signs of autism.

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The Human Phenotype Ontology in 2021

The Human Phenotype Ontology was launched in 2008 to provide a comprehensive logical standard to describe and computationally analyze phenotypic abnormalities found in human disease. The HPO is now a worldwide standard for phenotype exchange. The HPO has grown steadily since its inception due to considerable contributions from clinical experts and researchers from a diverse range of disciplines. Here, we present recent major extensions of the HPO for neurology, nephrology, immunology, pulmonology, newborn screening, and other areas.

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The Development and Feasibility of a Manualised Therapeutic Playgroup for Children with Developmental Delay

Playgroups are widely used throughout the Australian community yet understanding of their efficacy is hindered by inconsistent playgroup definitions and practice principles. This study aimed to develop, implement and evaluate the feasibility of a manualised therapeutic playgroup for children with developmental delay and their families using a three step process.

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Mapping tuberculosis prevalence in Africa using a Bayesian geospatial analysis

Worldwide, tuberculosis (TB) remains the leading cause of death from infectious diseases. Africa is the second most-affected region, accounting for a quarter of the global TB burden, but there is limited evidence whether there is subnational variation of TB prevalence across the continent. Therefore, this study aimed to estimate sub-national and local TB prevalence across Africa.

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Few sex differences in regional gray matter volume growth trajectories across early childhood

Sex-specific developmental differences in brain structure have been documented in older children and adolescents, with females generally showing smaller overall brain volumes and earlier peak ages than males. However, sex differences in gray matter structural development in early childhood are less studied. We characterized sex-specific trajectories of gray matter volume development in children aged 2–8 years.