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Diarrhoea remains a leading cause of mortality among children under five years of age, with over 99 % of deaths occurring in low- and middle-income countries. Poor water quality, inadequate sanitation, poverty, undernutrition, and limited healthcare access contribute to this lingering problem, together with emerging environmental stressors driven by climate change.
Human cutaneous leishmaniasis, a neglected tropical disease caused by Leishmania braziliensis, presents treatment challenges due to varying therapeutic responses. Current therapies often encounter limited efficacy and treatment failure, demanding a deeper understanding of immunopathogenesis and predictive markers.
Identifying individuals at high risk of type 1 diabetes (T1D) is crucial as disease-delaying medications are available. Here we report a microRNA (miRNA)-based dynamic (responsive to the environment) risk score developed using multicenter, multiethnic and multicountry ('multicontext') cohorts for T1D risk stratification. Discovery (wet and dry lab) analysis identified 50 miRNAs associated with functional β cell loss, which is a hallmark of T1D.
Nirsevimab is a long-acting monoclonal antibody used to prevent respiratory syncytial virus (RSV) infection in infants and high-risk children. During the 2024 RSV season in Western Australia, 21 922 doses were administered to infants entering their first season and 1221 doses to at-risk children. In this context, the selection and spread of escape variants are a potential concern. This study aimed to investigate nirsevimab binding site mutations using clinical and wastewater data.
Researchers from The Kids Research Institute Australia in Perth and Tulane University in New Orleans have developed sophisticated data modelling that could help eradicate malaria in Haiti.
Dr Alex Brown to take up a new appointment as Professor of Indigenous Genomics.
A youth mental health researcher aiming to map suicide hotspots and avert further suicides in WA has been awarded a prestigious fellowship from the Forrest Research Foundation.
Pioneering health consumer advocate Anne McKenzie AM has been awarded the National Health and Medical Research Council’s prestigious Consumer Engagement Award in recognition of an almost 30-year career.
A collaborative research team has secured federal funding to examine ways to improve the experience that children, adolescents and young people have when they present to hospital emergency departments for an acute mental health crisis with the aim of reducing the rate of youth suicide.
We want to hear from people across the WA community - about the big issues and concerns facing our children, young people, and their families. Share your voice and views to help guide our research for happy, healthy kids.