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Showing results for "early childhood"

Mandating COVID-19 vaccinations for children: Attitudes of Western Australian parents

Australian governments have used vaccine mandates to drive high uptake of routine childhood vaccines and adult Coronavirus Disease 2019 (COVID-19) and influenza vaccines. We sought to understand the attitudes of Western Australian parents regarding mandating COVID-19 vaccines for children, interviewing 44 parents of children aged up to 18 years between May and December 2021. Transcripts were analysed to ascertain parents' attitudes and sources of reasoning.

Novel coenzyme Q6 genetic variant increases susceptibility to pneumococcal disease

Acute lower respiratory tract infection (ALRI) remains a major worldwide cause of childhood mortality, compelling innovation in prevention and treatment. Children in Papua New Guinea (PNG) experience profound morbidity from ALRI caused by Streptococcus pneumoniae. As a result of evolutionary divergence, the human PNG population exhibits profound genetic variation and diversity. To address unmet health needs of children in PNG, we tested whether genetic variants increased ALRI morbidity. 

New approach to protecting bones in children with leukaemia shows rapid results

Preclinical research from the WA Comprehensive Kids Cancer Centre has revealed a promising new strategy to protect bone health in children with high-risk B-cell acute lymphoblastic leukaemia (B-ALL), showing that actively rebuilding bone may deliver faster and more effective protection against debilitating fractur

Dysregulated Notch Signaling in the Airway Epithelium of Children with Wheeze

The airway epithelium of children with wheeze is characterized by defective repair that contributes to disease pathobiology. Dysregulation of developmental processes controlled by Notch has been identified in chronic asthma. However, its role in airway epithelial cells of young children with wheeze, particularly during repair, is yet to be determined.

Cancer Preclinical Core

The Cancer Preclinical Core team provides standardised, high-quality preclinical evaluation to accelerate therapy development and generate the robust evidence needed to advance the most promising treatments into clinical trials.

International study looking at Kawasaki Disease

Perth researchers are leading an exciting new international study looking at genetic factors that may cause Kawasaki disease and the subsequent heart damage.

Seed grant preps world-first ear infection prevention therapy for human trials

The Kids Research Institute Australia has secured a State Government grant to prepare a nasal therapy designed to prevent childhood ear infections for a world-first clinical trial.

Researchers share in almost $1.8 million for groundbreaking child health respiratory research

Three researchers from the Wal-yan Respiratory Research Centre will share in almost $1.8 million in grants to continue groundbreaking research to tackle childhood asthma prevention and lung disease.

PhD scholarship

PhD Scholarship opportunities The Rio Tinto Children’s Diabetes Centre; A JDRF Global Centre of Excellence, (“the Centre”) based at The Kids Research

Meet Perth's final ENDIA participant

Australia’s biggest study into the causes of type 1 diabetes reached a significant milestone when its last Perth-based participant was born recently.