Sensitive measures of early lung disease are being integrated into therapeutic trials and clinical practice in cystic fibrosis (CF). The impact of ea…
Neutrophil elastase is a significant risk factor for structural lung disease in cystic fibrosis, and Pseudomonas aeruginosa airway infection is linke…
Preterm birth is associated with lifelong respiratory sequelae, yet our understanding of lung function trajectories across the lifespan remains limit…
Chronic, low-intensity air pollution exposure has been consistently associated with reduced lung function throughout childhood. However, there is lim…
The burden of bronchiectasis is disproportionately high in Aboriginal adults, with early mortality. Bronchiectasis precursors, that is, protracted ba…
Chest CT identifies children at an early age who have adverse long-term outcomes
Sensitive and non-invasive surveillance tools are needed for the clinical management of infants and preschool children with cystic fibrosis (CF). The…
In response to repeated lung infection in cystic fibrosis (CF), white blood cells called neutrophils ... result, neutrophil activity is a good indica…
Cystic fibrosis (CF) is characterized by small airway disease; but central airways may also be affected. We hypothesized that airway resistance estim…
Our work has identified a clinically relevant host-derived factor that may participate in shaping early events in the aetiology of CF respiratory dis…