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No detectable effects of acute tryptophan depletion on short-term immune system cytokine levels in healthy adultsThe acute tryptophan depletion condition did not result in significant changes to cytokine concentrations for the entire study sample
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Challenges in Accurately Assessing Prenatal Alcohol Exposure in a Study of Fetal Alcohol Spectrum Disorder in a Youth Detention CenterAccurately assessing prenatal alcohol consumption is exceptionally challenging when assessed retrospectively as part of a FASD assessment for a young person sentenced to detention
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Nicotine and other potentially harmful compounds in "nicotine-free" e-cigarette liquids in AustraliaThe aim of our investigation was to assess the chemical composition of a range of e-liquids available in Australia, focusing on nicotine and other potentially harmful compounds
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Emerging diabetes and metabolic conditions among Aboriginal and Torres Strait Islander young peopleCollaboration between clinicians and researchers is required to establish the prevalence and disease burden of type 2 diabetes among Indigenous young people
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Allergy alerts — The incidence of parentally reported allergies in children presenting for general anesthesiaOnly the minority of parent-reported allergies in pediatric surgical patients were specialist confirmed and likely to be clinically relevant
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Risk of Developmental Disorders in Children of Immigrant Mothers: A Population-Based Data Linkage EvaluationIncreased risk of autism spectrum disorder with intellectual disability and cerebral palsy with intellectual disability for mothers of some foreign-born groups
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Environmental and social determinants of acute rheumatic fever: a longitudinal cohort studyPrevention strategies in ARF endemic settings may be enhanced by targeting new members entering a community and children in environments of close contact
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Early life innate immune signatures of persistent food allergyEarly life innate immune dysfunction may represent a key immunological driver and predictor of persistent food allergy in childhood
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Exposure to chorioamnionitis alters the monocyte transcriptional response to the neonatal pathogen Staphylococcus epidermidisOur findings suggest that prenatal exposure to inflammation may alter the risk of sepsis in preterm infants partly by modulation of monocyte responses to pathogens
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PI3K activation in neural stem cells drives tumorigenesis which can be ameliorated by targeting the cAMP response element binding proteinOur findings present a novel mouse model for glioma demonstrating that the PI3K pathway is important for initiation of tumorigenesis