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Protein, exercise and hypo study

For this study, we want to see how much protein is necessary to prevent overnight hypos without causing high blood glucose levels.

Recruits needed for new tech study

Meet Sophie - she's Australia's first participant in the multi-site Advanced Hybrid Closed Loop study.

Managing the mental health impact of diabetes

Exploring the link between diabetes and mental health. Story by The West Australian featuring Dr Keely Bebbington.

James' brush with fame

Did you catch the kids’ takeover Telethon segment on the weekend? If so, you may have spied James Fernihough hanging out with Ch 7 television personality Andrew Denton in the The Kids Discovery Centre.

Kids connect at diabetes camp

Kids living with Type 1 Diabetes got to hang out with super heroes and like-minded peers at the Diabetes WA and Princess Margaret Hospital (now known as Perth Children’s Hospital) kids’ camp in Bicton recently.

Congratulations Vinutha

Congratulations to Dr Vinutha Shetty who has been awarded a Type 1 Diabetes Clinical Research Network’s Mentored Clinician Researcher Fellowship Award for 2017.

Perth's active T1D community

Despite the unseasonal weather, good turnouts were recorded for recent events organised by PMH and Diabetes WA.

Flt3L-mediated tumor cDC1 expansion enhances immunotherapy by priming stem-like CD8+ T cells in lymph nodes

Immune checkpoint blockade (ICB) evokes antitumor immunity through the reinvigoration of T cell responses. T cell differentiation status controls response, with less differentiated cells having an enhanced capacity to proliferate after ICB. Given that conventional type 1 dendritic cells (cDC1) maintain precursor exhausted T cells (TPEX), we hypothesized that expansion of cDC1s with Flt3L could enhance responses to ICB. 

A phase 3 study of safety and immunogenicity of V114, a 15-valent pneumococcal conjugate vaccine, followed by 23-valent pneumococcal polysaccharide vaccine, in children with HIV

To evaluate the safety and immunogenicity of V114 [15-valent pneumococcal conjugate vaccine (PCV) containing serotypes 1, 3, 4, 5, 6A, 6B, 7F, 9 V, 14, 18C, 19A, 19F, 22F, 23F, 33F], followed by 23-valent pneumococcal polysaccharide vaccine (PPSV23) 8 weeks later, in children with HIV.

Control of mitophagy initiation and progression by the TBK1 adaptors NAP1 and SINTBAD

Mitophagy preserves overall mitochondrial fitness by selectively targeting damaged mitochondria for degradation. The regulatory mechanisms that prevent PTEN-induced putative kinase 1 (PINK1) and E3 ubiquitin ligase Parkin (PINK1/Parkin)-dependent mitophagy and other selective autophagy pathways from overreacting while ensuring swift progression once initiated are largely elusive.