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Preparing for Life: Plasma Proteome Changes and Immune System Development During the First Week of Human LifeNeonates have heightened susceptibility to infections. The biological mechanisms are incompletely understood but thought to be related to age-specific adaptations in immunity due to resource constraints during immune system development and growth. We present here an extended analysis of our proteomics study of peripheral blood-plasma from a study of healthy full-term newborns delivered vaginally, collected at the day of birth and on day of life (DOL) 1, 3, or 7, to cover the first week of life. The plasma proteome was characterized by LC-MS using our established 96-well plate format plasma proteomics platform.
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Meta-analysis of the neural correlates of vigilant attention in children and adolescentsVigilant Attention (VA), defined as the ability to maintain attention to cognitively unchallenging activities over a prolonged period of time, is critical to support higher cognitive functions and many behaviours in our everyday life. Evidence has shown that VA rapidly improves throughout childhood and adolescence until young adulthood and tends to decline in older adulthood.
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Current Status of Schistosomiasis Control and Prospects for Elimination in the Dongting Lake Region of the People's Republic of ChinaSchistosomiasis japonica is an ancient parasitic disease that has severely impacted human health causing a substantial disease burden not only to the Chinese people but also residents of other countries such as the Philippines, Indonesia and, before the 1970s, Japan. Since the founding of the new People's Republic of China (P. R. China), effective control strategies have been implemented with the result that the prevalence of schistosomiasis japonica has decreased markedly in the past 70 years.
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Prenatal alcohol and tobacco use and the risk of depression in offspring at age of 17 years: findings from the Raine StudyPrenatal alcohol and tobacco exposures have been associated with adverse mental health consequences in offspring. The objective of this study was to test the associations between maternal prenatal alcohol and tobacco exposures and depressive symptoms in the offspring, adjusting for a wide range of potential confounders.
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Tackling the Burden of Osteoarthritis as a Health Care Opportunity in Indigenous Communities-A Call to ActionOsteoarthritis is a highly prevalent and disabling disease, causing a significant individual and socioeconomic burden worldwide. Until now, there has been a dearth of research exploring the impact of osteoarthritis in global Indigenous communities.
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The Australian and New Zealand Children's Haematology/Oncology Group Biobanking NetworkThe ANZCHOG-BN is a new biobank network in Australasia that was developed to improve and streamline access to high-quality pediatric and AYA cancer biospecimens
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Increased Use of Adrenaline in the Management of Childhood Anaphylaxis Over the Last DecadeThere was a significant improvement in the management of anaphylaxis after the introduction of intensified physician training programs
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Side effects of medications used to treat childhood interstitial lung diseaseInterstitial lung disease in children comprises a range of different rare diseases
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Excess stroke incidence in young Aboriginal people in South Australia: Pooled results from two population-based studiesThe excess stroke incidence in Aboriginal South Australians appears substantial, especially in those aged <55 years
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Maternal smoking and low family income during pregnancy as predictors of the relationship between depression and adiposity in young adultsWe aimed to investigate the influence of antenatal and postnatal factors on the increasing incidence of overweight/obesity and mental health disorders in young adults