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Risk of childhood acute lymphoblastic leukaemia following parental occupational exposure to pesticides

Risk of childhood acute lymphoblastic leukaemia following parental occupational exposure to pesticides.

Suppression of adrenomedullin contributes to vascular leakage and altered epithelial repair during asthma

The anti-inflammatory peptide, adrenomedullin (AM), and its cognate receptor are expressed in lung tissue, but its pathophysiological significance in airway...

Evaluation of a new measure of mood intolerance, the Tolerance of Mood States Scale (TOMS)

This research aimed to (i) validate a new measure of mood intolerance, the Tolerance of Mood States (TOMS) scale, and (ii) to examine associations between...

The developing respiratory tract and its specific needs in regard to ultrafine particulate matter exposure

Nanoparticles have unique physico-chemical properties compared to larger particles that have the potential to provide promising new possibilities for...

Vitamin D supplementation, moderate sun exposure, and control of immune diseases

There is considerable debate about the benefits of vitamin D supplementation for multiple sclerosis, allergic asthma, and type 1 diabetes.

Nanoparticles and Children's Lungs: Is there a need for caution?

Nanoparticle research is currently an area of considerable interest due to the potential applications both in industry and medicine.

Sex dimorphism in the relation between early adiposity and cardiometabolic risk in adolescents

Birth weight and childhood adiposity are associated with subsequent cardiovascular risk. We investigated the associations between metabolic clusters in young...

The anti-inflammatory actions of IL-4 in human monocytes are not mediated by IL-10, RP105 or the kinase activity of RIPK2

The anti-inflammatory actions of IL-4 in activated human monocytes may reflect transcriptional regulation of genes involved in TLR signaling pathways.

Progression of early structural lung disease in young children with cystic fibrosis assessed using CT

Cross-sectional studies implicate neutrophilic inflammation and pulmonary infection as risk factors for early structural lung disease in infants and young...

Variation in excess all-cause mortality by age, sex, and province during the first wave of the COVID-19 pandemic in Italy

Although previous evidence suggests that the infection fatality rate from COVID-19 varies by age and sex, and that transmission intensity varies geographically within countries, no study has yet explored the age-sex-space distribution of excess mortality associated with the COVID pandemic.