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Maternal smoking during pregnancy and the risk of childhood type 1 diabetes in Western Australia

The aim of this study was to investigate the association between maternal smoking during pregnancy and type 1 diabetes in the offspring, using complete...

Cyclical variation in the incidence of childhood type 1 diabetes in Western Australia (1985-2010)

The objective was to examine the incidence of childhood type 1 diabetes in Western Australia from 1985-2010.

Impact of Neuritin 1 (NRN1) polymorphisms on fluid intelligence in schizophrenia

Neuritin 1, an activity-regulated gene with multiple roles in neurodevelopment & synaptic plasticity, is linked to a subtype of schizophrenia.

Lost in translation: translational interference from a recurrent mutation in exon 1 of MECP2

Rett syndrome (RTT) is an X linked neuro-developmental disorder affecting mostly girls. Mutations in the coding region of MECP2 are found in 80% of classic...

$1 million boost to accelerate elimination of rheumatic heart disease in Western Australia

Efforts to eliminate rheumatic heart disease (RHD) have been significantly strengthened, with a $1 million grant awarded through the Future Health Research and Innovation Fund (FHRI) Spotlight Program.

1 in 3 young people in detention has alcohol related brain damage

About a third of young people in youth detention in Western Australia have Fetal Alcohol Spectrum Disorder (FASD), data has found.

Training vs competition blood glucose in people with type 1 diabetes

Participants needed for a research study to observe the influence of competition stress on the blood glucose and management strategies of people with T1D

A recipe for success in managing type 1 diabetes for teenagers

An innovative cooking program, the first of its kind in Australia, is being offered at Perth Children’s Hospital, combining nutrition education and practical cooking skills for teenagers living with type 1 diabetes (T1D).

WA teenager with type 1 diabetes on a mission to become a pro-cyclist

A wiry tall teenager, who was struggling somewhat with his blood glucose control, he turned up on his trusty bike, and we had something in common to talk about.

What goes up must come down: dynamics of type 1 interferon signaling across the lifespan

Type 1 interferons (T1IFNs) are typically expressed in low concentrations under homeostatic conditions, but upon pathogenic insult or perturbation of the pathway, these critical immune signaling molecules can become either protectors from or drivers of pathology. While essential for initiating antiviral defense and modulating inflammation, dysregulation of T1IFN signaling can contribute to immunopathology, making it and its associated pathways prime targets for immune evasion and disruption by pathogens.