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Research

Burkholderia pseudomallei evades Nramp1 (Slc11a1)- and NADPH oxidase-mediated killing in macrophages and exhibits Nramp1-dependent virulence gene expression

Here we show that transfected macrophages stably expressing wild-type Nramp1 (Nramp1+) control the net replication of B. thailandensis, but not B. pseudomallei.

Research

Evolving Identification of Blood Cells Associated with Clinically Isolated Syndrome: Importance of Time since Clinical Presentation and Diagnostic MRI

This study aimed to identify a CIS peripheral blood signature that may provide clues for potential immunomodulatory approaches early in disease

Research

The bioenergetics of inflammation: insights into obesity and type 2 diabetes

Diabetes mellitus is one of the most common chronic metabolic disorders worldwide, and its incidence in Asian countries is alarmingly high.

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Acute rheumatic fever and rheumatic heart disease

Acute rheumatic fever (ARF) is the result of an autoimmune response to pharyngitis caused by infection with group A Streptococcus.

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Trends in maternal and newborn health characteristics and obstetric interventions among Aboriginal and Torres Strait Islander mothers

Trends in maternal demographic characteristics, pre-existing medical conditions, pregnancy complications and neonatal characteristics were examined.

Research

Seasonal trivalent influenza vaccination during pregnancy and the incidence of stillbirth: Population-based retrospective cohort study

Although antenatal influenza vaccination is an important public health intervention for preventing serious infection in pregnant women and newborns, reported...

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How well can poor child development be predicted from early life characteristics? A whole-of-population data linkage study

A targeted program would have the potential to prevent one-quarter of the cases of being vulnerable on two or more AEDC domains at age five

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Soft neurological signs and prenatal alcohol exposure: A population-based study in remote Australia

Soft neurological signs were more common in children with prenatal alcohol exposure or FASD, consistent with the known neurotoxic effect of PAE

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Comparing risks of cerebral palsy in births between Australian Indigenous and non-Indigenous mothers

Indigenous infants have a higher risk of CP than non-Indigenous infants, especially postneonatal CP.

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Maternity-care: measuring women’s perceptions

Development of an instrument to assess women's perception of their entire maternity-care experience