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Research

Research in psychopharmacology in children and adolescents is an area of growing interest with numerous newer modalities becoming available in recent years. Nevertheless, it still lags significantly behind research in adult psychopharmacology although, in the last decade, the gap is beginning to be bridged with FDA approval for newer agents for the paediatric age group.

Research

Despite the wide use of parenteral nutrition (PN) in neonatal intensive care units (NICU), there is limited evidence regarding the optimal time to commence PN in term and late preterm infants.

Research

The specific role of chromatin modifying factors in the timely execution of transcriptional changes in gene expression to regulate organ size remains largely unknown. Here, we report that in Drosophila melanogaster depletion of the histone demethylase dLsd1 results in the reduction of wing size. dLsd1 depletion affects cell proliferation and causes an increase in DNA damage and cell death.

Research

Difficulties in executive functioning (EF) can result in impulsivity, forgetfulness, and inattention. Children living in remote/regional communities are particularly at risk of impairment in these cognitive skills due to reduced educational engagement and poorer access to interventions. This vulnerability has been exacerbated by the COVID-19 pandemic and strategies are needed to mitigate long-term negative impacts on EF.

Research

Clinical management of breast cancer (BC) metastasis remains an unmet need as it accounts for 90% of BC-associated mortality. Although the luminal subtype, which represents >70% of BC cases, is generally associated with a favorable outcome, it is susceptible to metastatic relapse as late as 15 years after treatment discontinuation.

Research

Although previous evidence suggests that the infection fatality rate from COVID-19 varies by age and sex, and that transmission intensity varies geographically within countries, no study has yet explored the age-sex-space distribution of excess mortality associated with the COVID pandemic.

Research

Social media may play a role in the "contagion" mechanism thought to underpin suicide clusters. Our pilot case-control study presented a novel methodological approach to examining whether Facebook activity following cluster and non-cluster suicides differed.

Applications are open for our 2025 Honours and Masters Scholarships with the purpose of providing funding for students to develop and support their type 1 diabetes (T1D) related research.

News & Events

Good planning and communication between families and schools is very important to ensure children are safe and supported. With the new school year underway, hear from our Social Work team with their top tips on managing the start of a new school year.

News & Events

What is a Carboyhdrate - Diabetes Nutrition Video We know there is a lot of information out there about food and nutrition and that parents want to

News & Events

Families gathered in the autumn sunshine to celebrate ORIGINS

News & Events

The Kids Joondalup will be the new home for the ORIGINS research and data teams

News & Events

Systematic review explores engagement levels of digital tools during the perinatal period

News & Events

Calling all budding artists - submit your child's artwork to win!

News & Events

ORIGINS participated in the inaugural Wadjak Northside Social Emotional Wellbeing Expo on 24 October at the Wadjak Northside Aboriginal Community Centre.