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Research

Tonsil organ model to evaluate carriage, disease mechanisms and therapeutic interventions for treatment and prevention of GAS infections

Tim Barnett PhD Head, Strep A Pathogenesis and Diagnostics timothy.barnett@thekids.org.au Head, Strep A Pathogenesis and Diagnostics Tim has worked

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Swimming pools in remote Aboriginal communities

Providing remote communities with access to chlorinated swimming pools has been considered as a possible strategy for reducing ear and skin infection rates...

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Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990-2010: A systematic analysis

Measuring disease and injury burden in populations requires a composite metric that captures both premature mortality and the prevalence and severity of...

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Working towards a Group A Streptococcal vaccine: Report of a collaborative Trans-Tasman workshop

This paper is a report on progress towards a joint Australian and New Zealand vaccination program for Group A Streptococcus bacteria, which causes serious...

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Attendances during the First 12 Months of Life for Aboriginal Children in Five Remote Communities of Northern Australia

The median number of presentations per child in the first year of life was 21 with multiple reasons for presentation.

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Invasive Staphylococcus aureus Infections in Children in Tropical Northern Australia

We conducted a retrospective review for all cases of S aureus bacteremia and sterile site infections, for children under 15 years, in northern Australia over...

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Benzathine penicillin G for the management of RHD: Concerns about quality and access, and opportunities for intervention and improvement

Benzathine penicillin G is an important antibiotic for the treatment and prevention of group A streptococcal infections associated with rheumatic fever and...

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Rheumatic heart disease in Indigenous young peoples

Indigenous children and young peoples live with an inequitable burden of acute rheumatic fever and rheumatic heart disease. In this Review, we focus on the epidemiological burden and lived experience of these conditions for Indigenous young peoples in Australia, New Zealand, and Canada. We outline the direct and indirect drivers of rheumatic heart disease risk and their mitigation.

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Reference exome data for Australian Aboriginal populations to support health-based research

Our data set provides a useful reference point for genomic studies on Aboriginal Australians