Keywords:
adolescents; biological impact; cardiovascular consequences; glucose counter-regulation; iatrogenic hypoglycaemia; risk factors; type 1 diabetes; type 2 diabetes
Abstract:
Iatrogenic hypoglycaemia is one of the main limiting factors in the glycaemic management of diabetes. It causes negative biological, psychological, and social consequences in most people with type 1 diabetes and in many with advanced type 2 diabetes. This chapter explores physiological homeostatic mechanisms that prevent hypoglycaemia through glucose counter-regulation, before discussing specific acquired defects of glucose counter-regulation in diabetes, which provides an insight into risk factors for hypoglycaemia.