MetaNeb Versus Usual Care During Exacerbations of Cystic Fibrosis: An RCT

During exacerbations, when symptom and treatment burden are increased, individuals with cystic fibrosis (CF) are likely to prefer airway clearance techniques (ACTs) that require minimal effort. Therefore, in adults with CF who were hospitalised with an exacerbation, we sought to compare the effect of the MetaNeb with usual ACTs on respiratory function and expectorated sputum.

Citation:
Chapman N, Cavalheri V, Smith EF, Wood J, Garratt LW, Mulrennan S, et al. MetaNeb Versus Usual Care During Exacerbations of Cystic Fibrosis: An RCT. Respirology. 2025.

Keywords:
Airway clearance techniques; cystic fibrosis; physiotherapy

Abstract:
During exacerbations, when symptom and treatment burden are increased, individuals with cystic fibrosis (CF) are likely to prefer airway clearance techniques (ACTs) that require minimal effort. Therefore, in adults with CF who were hospitalised with an exacerbation, we sought to compare the effect of the MetaNeb with usual ACTs on respiratory function and expectorated sputum.