Tumor site-directed A1R expression enhances CAR T cell function and improves efficacy against solid tumors

Citation:
Sek K, Chen AXY, Cole T, Armitage JD, Tong J, ……… Waithman J, Parish IA, et al. Tumor site-directed A1R expression enhances CAR T cell function and improves efficacy against solid tumors. Nat Commun. 2025;16(1).

Keywords:
CRISPR-Cas Systems; cell lines; tumours; immunotherapy; genetics; neoplasms; immunology; therapy; aednosine A2A; chimeric antigen; T-lymphocytes