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Distinct Enterovirus Antigen Landscape in Children With Islet Autoimmunity

Enteroviruses (EVs) have long been implicated in the development of islet autoimmunity (IA) and type 1 diabetes. However, given the ubiquity of EV infections in children, disease susceptibility is likely driven by host-specific immune responses rather than viral exposure alone.

Citation:
Delgado-Corrales B, Fingerhut L, ……. Davis EA, Hamilton-Williams EE, ……. Haynes A, Huynh T,  et al. Distinct Enterovirus Antigen Landscape in Children With Islet Autoimmunity. Diabetes. 2026;75(4):738-47. 

Keywords:
Antibodies; immunology; autoimmunity; diabetes mellitus type 1; enterovirus infections; Islets of Langerhans

Abstract:
Enteroviruses (EVs) have long been implicated in the development of islet autoimmunity (IA) and type 1 diabetes. However, given the ubiquity of EV infections in children, disease susceptibility is likely driven by host-specific immune responses rather than viral exposure alone.