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Exploring the utility of indirect calorimetry to optimise nutrition in paediatric intensive care (ICONIC-1): a prospective observational cohort study protocol

The imprecision of predictive equations has led to recommendations for the use of indirect calorimetry to determine measured energy expenditure in the paediatric intensive care unit. However, the feasibility of newer devices, such as the QNRG+ and the impact of IC-guided nutrition delivery on patient outcomes remains unclear.

Citation:
Farrell T, Douglas K, Weiss H, ……. Cooper MN, Joosten KFM, ……. Laird P. Exploring the utility of indirect calorimetry to optimise nutrition in paediatric intensive care (ICONIC-1): a prospective observational cohort study protocol. Intensive Care Med. 2026;4(1).

Keywords:
Pediatric intensive care; Critical care; Skeletal muscle ultrasound; Body composition; Bio-impedance analysis

Abstract:
The imprecision of predictive equations has led to recommendations for the use of indirect calorimetry to determine measured energy expenditure in the paediatric intensive care unit. However, the feasibility of newer devices, such as the QNRG+ and the impact of IC-guided nutrition delivery on patient outcomes remains unclear.