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Glucagon-Like Peptide-1 Receptor Agonists in the Management of Mitochondrial Diabetes in an Adolescent: A Case Report

Mitochondrial diabetes is rare and typically treated with dietary intervention and oral hypoglycaemic agents. Most require insulin. Novel treatments are available but are not well characterised.

Citation:
Hayes E, Nillsen A, Rowe PW, Siafarikas A, Abraham MB. Glucagon-Like Peptide-1 Receptor Agonists in the Management of Mitochondrial Diabetes in an Adolescent: A Case Report. Horm Res Paediatr. 2026. 

Keywords:
GLP-1RA; Mitochondrial diabetes; Mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes; Semaglutide

Abstract:
Mitochondrial diabetes is rare and typically treated with dietary intervention and oral hypoglycaemic agents. Most require insulin. Novel treatments are available but are not well characterised.