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The Courage to Continue: the Staphylococcus aureus Network Adaptive Platform Trial for Pediatrics and Youth

Citation:
Bowen AC, Campbell AJ. The Courage to Continue: the Staphylococcus aureus Network Adaptive Platform Trial for Pediatrics and Youth. J Pediatric Infect Dis Soc. 2026;15(8).

Keywords:
Staphylococcus aureus; adolescents; children; neonates; randomized controlled trial

Abstract:
The Staphylococcus aureus Network Adaptive Platform trial is a whole-of-life infectious disease trial. Recently, results for the methicillin-susceptible Staphylococcus aureus domain in adults showed cefazolin is non-inferior to (flu)cloxacillin for S. aureus bacteremia. The trial continues in children. Here the investigators outline why.