Reports and Findings

Impact of social disadvantage on cerebral palsy severity

In Australia, socio-economic disadvantage at birth impacts adversely on cerebral palsy severity at age 5 years

Effect of combining pre-exercise carbohydrate intake and repeated short sprints on the blood glucose response to exercise in young individuals with Type 1 diabetes

When carbohydrates are ingested prior to moderate-intensity exercise, adding repeated sprints is not significantly detrimental to glycaemic management

Developmental vulnerabilities in children of chronically ill parents: A population-based linked data study

Maternal chronic illness is associated with an increased risk of poor developmental outcomes for children, particularly daughters

Intraseason decline in influenza vaccine effectiveness during the 2016 southern hemisphere influenza season: A test-negative design study and phylogenetic assessment

Overall, the 2016 influenza vaccine showed good protection against laboratory-confirmed infection among general practice patients

Impact of influenza on hospitalization rates in children with a range of chronic lung diseases

This large population-based study suggests a significant healthcare burden associated with influenza in children with a range of chronic lung diseases

Postvaccination Febrile Seizure Severity and Outcome

Vaccine-proximate febrile seizures accounted for a small proportion of all febrile seizures hospital presentations

Single-breath washout and association with structural lung disease in children with cystic fibrosis

Acinar ventilation inhomogeneity measured by single-breath washout was not associated with structural lung disease on CT

Normative data of muscle fiber diameter of vastus lateralis during childhood: a field test

This short report highlights the requirement for contemporary age-specific normative data from a larger number of biopsies, including typically developing children

Multiple risk exposures for reading achievement in childhood and adolescence

Across 6 years of school, multiple risk-exposed children lagged behind low risk-exposed children in the order of years of lost gains in reading achievement

novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunction

This study thus identified a novel small molecule that rapidly kills MLL-rearranged leukemia cells by targeting a metabolic vulnerability