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Research
Multiple breath washout cannot be used for tidal breath parameter analysis in infantsThere are differences in tidal breathing parameters during multiple breath washout testing with SF6 gas mixture in infants
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The impact of Influenza infection during early life on immune developmentThis study will investigate the why disease is worse in infants and how early life viral infection impacts the developing immune system.
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Consensus statement for inert gas washout measurement using multiple- and single- breath testsInert gas washout tests, performed using the single- or multiple-breath washout technique, were first described over 60 years ago.
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Targeting the mucosal immune system in a pregnant mouse model to prevent experimental allergic airways disease in the offspringStudies in Europe show exposure of pregnant women to high levels of microbial products stimulate immune function maturation in their offspring
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The Global Asthma Network: Understanding asthma in urban and regional Western AustraliaRachel Graham Alexandra Foong Hall Whelan BSc (hons), PhD, MBiostat BAppSci PhD CRFS FANZSRS FThorSoc FERS BSc, MPH Honorary Research Associate
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The cellular effects of estrogen on allergic asthmaThe study aims to identify the mechanism for this so that this knowledge can be used to better treat asthma and allergies in both males and females.
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Association between early bacterial carriage and otitis media in Aboriginal and non-Aboriginal childrenStreptococcus pneumoniae (Pnc), nontypeable Haemophilus influenzae (NTHi) and Moraxella catarrhalis (Mcat) are the most important bacterial pathogens...
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Mechanisms of IgE sensitizationThis project investigates how cells of the immune system respond to substances to cause allergies to help develop new treatments.
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The clinical utility of lung clearance index in early cystic fibrosis lung disease is not impacted by the number of multiple-breath washout trialsThis study aimed to determine if relationships between LCI and clinical outcomes of CF lung disease differ when only two acceptable MBW trials are assessed.
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Attenuation of maternal inflammatory responses during pregnancy to promote normal immune and behavioral outcomes in the offspringThis study will identify how the immune system contributes to neurodevelopmental outcomes and will investigate the use of an agent from traditional medicines.
casual research assistant kimberley
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Long-term derangement of antigen presenting cell populations in the respiratory tract following Influenza A infectionThis project investigates how different populations of cells within the respiratory tract immune system are altered during a viral infection.
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Finding the cellular explanation for recurrent asthma exacerbationsThis study is designed to identify the specific unique immune cell response that occurs in these children with recurrent disease.
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Early biomarkers predictive of autismThis study aims to investigate the cellular and molecular profiles of the immune system in infants at high/low risk for Autism, as determined through clinical assessment.
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Role of stem cell precursors in tissuesWe have recently published a paper identifying precursor populations in peripheral lung (2017), and have also discovered that these populations can be found in multiple tissues.
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Mapping changes in immune cell populations in gestational tissues over the course of pregnancyThis is a strategic “pilot” project in which we are seeking basic information on the immune cell content of gestational tissues.