In February 2025, Australia introduced maternal vaccination with bivalent respiratory syncytial virus prefusion F protein-based vaccine (RSVpreF) in…
The emergence of the SARS-CoV-2 Omicron variant in late 2021 led to widespread infection in Australian children, many unvaccinated. The breadth and m…
Intranasal vaccines offer a needle-free strategy to enhance immunity to respiratory infections. We investigated the mechanism of action of a novel in…
Encephalitis is inflammation of the brain parenchyma with heterogenous aetiology and presentation. In children, it often leads to short-term residual…
Australia introduced a hybrid Respiratory Syncytial Virus (RSV) Maternal and Infant Protection Program (RSV-MIPP) in 2025, using National Immunisatio…
PICOBOO is a randomised, adaptive trial evaluating the immunogenicity and reactogenicity of licensed COVID-19 booster vaccines in immunocompetent ind…
Waning immunity after acellular pertussis (aP) vaccines shown in pertussis outbreaks highlights the need for more effective aP vaccines.
Previous research has shown that immune development during the first week of life, i.e. ontogeny, is progressive, consistent and robust, involving la…
Although evidence supports clinicians to "safely do less" for febrile infants assessed as low risk of serious bacterial infection (SBI), early discha…
The predisposition to food allergy development and the induction of allergen-specific immune responses appears to be initiated early in infancy. Earl…