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Research
Effectiveness of trivalent flu vaccine in healthy young childrenThis paper reports some of the findings from the Western Australian Influenza Vaccine Effectiveness Study, commenced in 2008, to evaluate a program providing...
Research
Virus detection and its association with symptoms during influenza-like illness in a sample of healthy adults enrolled in a randomised controlled vaccine trialViral respiratory infections are associated with significant morbidity and mortality.
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No role for neutrophil elastase in influenza-induced cellular recruitment, cytokine production or airway hyperresponsiveness in micePrevious studies have suggested that in vitro modulation of neutrophil chemokines and inflammatory cytokines by neutrophil elastase (NE) does not translate to t
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The impact of Influenza infection during early life on immune developmentThis study will investigate the why disease is worse in infants and how early life viral infection impacts the developing immune system.
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Influenza vaccination among pregnant women in two hospitals in Sydney, NSW: what we can learn from women who decline vaccinationPregnant women are recognised as being at risk of serious illness from influenza. Despite this, and longstanding national recommendations for vaccination in pregnancy, vaccine uptake remains suboptimal. This study aims to determine factors associated with women declining influenza vaccination in pregnancy.
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Parainfluenza Virus Infection in an Australian Community-based Birth CohortIn a community-based birth cohort of 158 Australian infants followed to age 2 years, the incidence rate of human parainfluenza virus (HPIV) was 0.42 (95% CI = 0.33, 0.54) episodes per child-year with episodes occurring year-round, peaking in the spring season.
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Intraseason decline in influenza vaccine effectiveness during the 2016 southern hemisphere influenza season: A test-negative design study and phylogenetic assessmentOverall, the 2016 influenza vaccine showed good protection against laboratory-confirmed infection among general practice patients
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Impact of influenza on hospitalization rates in children with a range of chronic lung diseasesThis large population-based study suggests a significant healthcare burden associated with influenza in children with a range of chronic lung diseases
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Influenza vaccine effectiveness and uptake in children at risk of severe diseaseParticipation in the preschool influenza vaccination program remains low with parents unconvinced of the benefits and safety of influenza vaccine
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How immunity shapes the long-term dynamics of influenza H3N2Since its emergence in 1968, influenza A H3N2 has caused yearly epidemics in temperate regions. While infection confers immunity against antigenically similar strains, new antigenically distinct strains that evade existing immunity regularly emerge ('antigenic drift'). Immunity at the individual level is complex, depending on an individual's lifetime infection history.
News & Events
Who are our technology researchers and what do they do?A new Q&A series focusing on the different research themes within the Children’s Diabetes Centre - technology.
News & Events
Recruits wanted for water immersion studyThis University of Western Australia study, being conducted by a PhD student who is working with the Children's Diabetes Centre, aims to determine for the first time whether head out of water immersion or water-based exercise affects blood glucose levels in people with type 1 diabetes.
News & Events
Science Week at the Discovery CentreThe Kids Discovery Centre is celebrating National Science Week 2020 (August 17-21) with several exciting programs