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Clinical Trials, Platforms & Cohorts

Learn more about all of the Clinical Trials, Platforms & Cohorts at the Wal-yan respiratory centre.

Fighting pseudomonas aeruginosa and nontypeable

Fighting pseudomonas aeruginosa and nontypeable haemophilus influenzae biofilms with host defence peptide as a novel step forward in the treatment of

Transplacental Innate Immune Training via Maternal Microbial Exposure: Role of XBP1-ERN1 Axis in Dendritic Cell Precursor Programming

We recently reported that offspring of mice treated during pregnancy with the microbial-derived immunomodulator OM-85 manifest striking resistance to allergic airways inflammation, and localized the potential treatment target to fetal conventional dendritic cell (cDC) progenitors. Here, we profile maternal OM-85 treatment-associated transcriptomic signatures in fetal bone marrow, and identify a series of immunometabolic pathways which provide essential metabolites for accelerated myelopoiesis.

A method for the generation of large numbers of dendritic cells from CD34+ hematopoietic stem cells from cord blood

Neonatal dendritic cells generated form CD34+ cord blood progenitors have a higher inflammatory potential when exposed to viral than bacterial related stimuli

Single cell transcriptomics reveals cell type specific features of developmentally regulated responses to lipopolysaccharide between birth and 5 years

Human perinatal life is characterized by a period of extraordinary change during which newborns encounter abundant environmental stimuli and exposure to potential pathogens. To meet such challenges, the neonatal immune system is equipped with unique functional characteristics that adapt to changing conditions as development progresses across the early years of life, but the molecular characteristics of such adaptations remain poorly understood.

Children’s regenerative and genetic medicine program

The project aims to build capacity in regenerative medicine for children with respiratory diseases.

Chinese immigrants in Australia at higher risk of allergies, research shows

Chinese immigrants who live in a Western environment like Australia have an increased risk of allergies, hay fever and asthma, new research led by Curtin University and The Kids Research Institute Australia has found.

The Wal-yan Respiratory Research Centre turns three!

As the Wal-yan Respiratory Research Centre turns three, we celebrate our achievements, and say thank you to our amazing community.

Wal-yan researchers to present at largest respiratory meeting in the world

A large contingent of researchers from the Wal-yan Respiratory Research Centre are heading to Spain in September to participate in the European Respiratory Society (ERS) International Congress – the largest respiratory meeting in the world.