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Altered regulatory T-cell fractions and Helios expression in clinically isolated syndrome: clues to the development of multiple sclerosisThese results indicate that T regulatory (Treg) and follicular T regulatory (Tfr) impairment is an early feature in MS.
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Creating community indicators for early childhood development: challenges and innovations from the kids in communities studyThe community (or neighbourhood) is seen as a potential point of intervention for improving early childhood development outcomes through place-based approaches targeting all children. Yet there are insufficient robust data to guide policy and practice. Developing community factors for early childhood development is one way to facilitate more informed, evidence-based community action. This paper discusses the methodological learnings from the Kids in Communities Study, an Australian investigation into community-level factors important for early childhood development, including some of the challenges and innovations associated with the measurement and development of indicators.
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Adolescent Bystander Behavior in the School and Online Environments and the Implications for Interventions Targeting CyberbullyingThe aim of this study was to add to the emerging knowledge about the role of bystanders in cyberbullying.
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Fetal alcohol spectrum disorder in Australia: Practice guidelines for diagnosis and managementFetal alcohol spectrum disorder in Australia: Practice guidelines for diagnosis and management
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A longitudinal study of natural antibody development to pneumococcal surface protein A families 1 and 2 in Papua New Guinean Highland children: a cohort studyPneumococcal surface protein A is immunogenic and natural anti-PspA immune responses are acquired through exposure and develop with age
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How can clinical ethics guide the management of comorbidities in the child with Rett syndrome?This paper reviews the disorder Rett syndrome and evidence for the management of scoliosis and poor growth within a clinical ethics framework
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Quantitative and qualitative insights into the experiences of children with Rett syndrome and their familiesEarly presentation of Rett syndrome, including regression and challenges for families seeking a diagnosis
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Identification of genes differentially regulated by vitamin D deficiency that alter lung pathophysiology and inflammation in allergic airways diseaseVitamin D deficiency exacerbates house dust mite-induced inflammation and alterations in lung structure and function
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Vitamin D and allergic airway disease shape the murine lung microbiome in a sex-specific mannerMaintaining sufficient vitamin D is necessary for optimal lung health, and vitamin D may modulate the lung microbiome in a sex-specific fashion
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Comparative analyses of whole genome sequences of Leishmania infantum isolates from humans and dogs in northeastern BrazilOverall the analyses do not suggest individual sequence variants account for differences in clinical outcome or adaptation to different hosts.