This chapter describes the epidemiology, pathogenesis, clinical manifestations, diagnostic criteria, and management principles of acute rheumatic fev…
Rheumatic heart disease (RHD) is responsible for a significant burden of cardiovascular morbidity and mortality, and remains the most common cause of…
Seven female individuals with multiple congenital anomalies, developmental delay and/or intellectual disability have been found to have a genetic var…
Patients with congenital heart disease (CHD) are identified in 1% of live births. Improved surgical intervention means many patients now survive to a…
Kawasaki disease is characterized by increased inflammation
To determine the incidence, serotype distribution and clinical outcomes of invasive pneumococcal disease in children with acute lymphoblastic leukaem…
Mosaic Darier disease flaring following allogeneic stem cell transplant
drug; rare disease (RD); rare disease diagnosis; rare disease registry framework; rare disease research
renowned for her pioneering work in mitochondrial disease and synthetic biology, has developed paradigm-shifting ... work focused on reducing the chr…
We aim to assess the impact of interpregnancy intervals on maternal and child health outcomes in high-income countries