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In vitro liver models combined with metabolomics approaches offer promising alternatives to animal testing in toxicology. In this study, we investigated concentration-dependent effects of hydrogen peroxide on the intra- and extracellular metabolome of HepG2 cells using 1H Nuclear Magnetic Resonance spectroscopy.
The Wal-yan Respiratory Research Centre is made up of multi-disciplinary teams that are committed to improving the lives of children and their families living with respiratory disease.
Focuses on understanding and improving early childhood health and development to set the foundation for lifelong wellbeing. By addressing factors from pregnancy through early years, this theme aims to optimise health outcomes from the very start.
Scabies infection is associated with heightened total IgE immunoglobulin and IgE antibodies to scabies antigens, with both being extremely high for crusted scabies patients. The IgE antibodies cross-react with house dust mite allergens with high reactivity found to the minor allergen arginine kinase.
The declining mental health of youth in late adolescence and early adulthood represents a serious public health concern, resulting in substantial symptom burden, mortality, and societal cost. Despite this, youth with clinical mental illnesses show poor engagement with mental health services.
This study examined how mental health clinicians conceptualise, assess, and treat dissociation in children and adolescents, and examined their confidence in working with these presentations to inform clinical practice.
Plastic pyrolysis oil, which can be produced with similar properties as diesel fuel (plastic diesel), can be used as an alternative to mineral diesel (ULSD) to run a diesel engine. This presents a potential method for recycling waste plastic. Typically plastic diesel is blended with mineral diesel, and oxygenated fuel additives such as ethers added to improve resulting fuel properties.