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DeepCAGE transcriptomics identify HOXD10 as a transcription factor regulating lymphatic endothelial responses to VEGF-C

The role of HOXD10 in the regulation of VEGFR-3 signaling in lymphatic endothelial cells, and in the control of lymphangiogenesis and permeability

Differential gene network analysis for the identification of asthma-associated therapeutic targets in allergen-specific T-helper memory responses

Differential network analysis of allergen-induced CD4 T cell responses can unmask covert disease-associated genes and pin point novel therapeutic targets

Western environment/lifestyle is associated with increased genome methylation and decreased gene expression in Chinese immigrants living in Australia

Chinese immigrants living in Australia for a longer period of time have increased overall genome methylation and decreased overall gene expression

Consensus communication on early peanut introduction and the prevention of peanut allergy in high-risk infants

The purpose of this article is to highlight emerging evidence for existing allergy prevention guidelines regarding potential benefits of supporting early...

Chronic cat allergen exposure induces a Th2 cell-dependent IgG4 response related to low sensitization

This study evaluated the relationship between cat allergen–specific biomarkers in adults with cat allergy with and without cat ownership.

Maternal vitamin D deficiency alters fetal brain development in the BALB/c mouse.

Prenatal exposure to vitamin D is thought to be critical for optimal fetal neurodevelopment, yet vitamin D deficiency is apparent in a growing proportion of...

The increasing prevalence of reported diagnoses of childhood psychiatric disorders: a descriptive multinational comparison

The objective of this study is to compare the time trend of reported diagnoses of autism spectrum disorder, hyperkinetic disorder, Tourette's syndrome, and...

Risk of cancer among children with birth defects: A novel approach

This novel approach aimed to prevent inflated hazard ratios arising from reverse causation, and allow identification of associations beyond those already...

Birthweight and childhood cancer: Preliminary findings from the international childhood cancer cohort consortium (I4C)

Background Evidence relating childhood cancer to high birthweight is derived primarily from registry and case-control studies.

Developments in the field of allergy in 2014 through the eyes of Clinical and Experimental Allergy

The pathogenesis of asthma continues to be a major topic of interest to our authors with reviews and original papers on the role of viruses, mechanisms of...