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Showing results for "clinical trials"
The Opportunity BEAT CF is a national, 5 year, multi-centre platform trial to improve the management of children and adults with Cystic Fibrosis. Be
Research
Patient positioning and its impact on perioperative outcomes in children: A narrative reviewPatient positioning interacts with a number of body systems and can impact clinically important perioperative outcomes. In this educational review, we present the available evidence on the impact that patient positioning can have in the pediatric perioperative setting. A literature search was conducted using search terms that focused on pediatric perioperative outcomes prioritized by contemporary research in this area.
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Difficult intubation in syndromic versus nonsyndromic forms of micrognathia in childrenWe investigated how syndromic versus nonsyndromic forms of micrognathia impacted difficult intubation outcomes in children. Primary outcome was the first-attempt success rate of tracheal intubation, secondary outcomes were number of intubation attempts and complications. We hypothesized that syndromic micrognathia would be associated with lower first-attempt success rate.
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Reliability of the Commonly Used and Newly-Developed Autism MeasuresThe aim of the present study was to compare scale and conditional reliability derived from item response theory analyses among the most commonly used, as well as several newly developed, observation, interview, and parent-report autism instruments.
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Impact of a revised postoperative care plan on pain and recovery trajectory following pediatric tonsillectomyA previous cohort of adenotonsillectomy patients at our institution demonstrated moderate-severe post-tonsillectomy pain scores lasting a median (range) duration of 6 (0-23) days and postdischarge nausea and vomiting affecting 8% of children on day 1 following surgery. In this subsequent cohort, we evaluate the impact of changes to our discharge medication and parental education on post-tonsillectomy pain and recovery profile.
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Effect of different lung recruitment strategies and airway device on oscillatory mechanics in children under general anaesthesiaAtelectasis has been reported in 68 to 100% of children undergoing general anaesthesia, a phenomenon that persists into the recovery period. Children receiving recruitment manoeuvres have less atelectasis and fewer episodes of oxygen desaturation during emergence. The optimal type of recruitment manoeuvre is unclear and may be influenced by the airway device chosen.
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Developmental vitamin D deficiency produces behavioral phenotypes of relevance to Autism in an animal modelHere we investigate these features in an animal model related to autism spectrum disorder - the DVD-deficient rat
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Brief Report: An Exploratory Study of the Diagnostic Reliability for Autism Spectrum DisorderWe conducted a study that examined the concordance of diagnoses between a multidisciplinary assessment team and a range of clinicians in Australia.
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Obesity and associated factors in youth with an autism spectrum disorderPrevalence of overweight/obesity in children and youth with autism spectrum disorder, and associations between weight status and range of factors
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A multicentre, retrospective audit of fosfomycin use for urinary tract infections in Australian children and adolescentsUrinary tract infections (UTIs) due to MDR organisms are increasingly common. The lack of paediatric data on efficacious antibiotics makes UTI treatment particularly challenging. Data on the efficacy of fosfomycin use for UTI in children are variable.