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The effects of birth spacing on early childhood development in high-income nations: A systematic review

This study aimed to systematically review the literature on the associations between birth spacing and developmental outcomes in early childhood (3–10 years of age). Studies examining the associations between interpregnancy intervals and child development outcomes during and beyond the perinatal period have not been systematically reviewed.

Temporal dynamics of B cell dysfunction and EBV responses in early multiple sclerosis

Multiple sclerosis (MS) is an incurable condition where a person’s immune system mistakenly attacks their own brain and spinal cord.

Community Conversation "What support do families with early-stage T1D need?"

What support do families with early-stage T1D need? Screening for the risk of developing T1D is now an option. But as exciting as screening is, we

Event: Getting it Right in the Early Years: Our Collective Responsibility

Hear from CoLab Director Professor Donna Cross as we provide an overview of the early childhood landscape and launch the CoLab Strategic Framework.

3D face scanner could improve early diagnosis for kids with autism

Can you see signs of autism in a child's facial features? Telethon Kids researchers have acquired new face scanning technology to help answer this question.

Changes to the Gut Microbiome in Young Children Showing Early Behavioral Signs of Autism

The human gut microbiome has increasingly been associated with autism spectrum disorder (ASD), which is a neurological developmental disorder, characterized by impairments to social interaction.

Placental Transcription Profiling in 6–23 Weeks’ Gestation Reveals Differential Transcript Usage in Early Development

The human placenta is a rapidly developing transient organ that is key to pregnancy success. Early development of the conceptus occurs in a low oxygen environment before oxygenated maternal blood begins to flow into the placenta at ~10–12 weeks’ gestation. This process is likely to substantially affect overall placental gene expression. Transcript variability underlying gene expression has yet to be profiled.

The longitudinal relationship between BOLD signal variability changes and white matter maturation during early childhood

Intra-individual transient temporal fluctuations in brain signal, as measured by fMRI blood oxygenation level dependent (BOLD) variability, is increasingly considered an important signal rather than measurement noise.

Associations Among Early Stimulation, Stunting, and Child Development in Four Countries in the East Asia–Pacific

This study examined associations among preschool attendance, home learning activities, stunting status, and early child development using data from the validation study of the East Asia–Pacific Early Child Development Scales (EAP-ECDS).

Gender gaps in cognitive and social-emotional skills in early primary grades: Evidence from rural Indonesia

This paper examines the magnitude and source of gender gaps in cognitive and social-emotional skills in early primary grades in rural Indonesia. Relative to boys, girls score more than 0.17 SD higher in tests of language and mathematics (cognitive skills) and between 0.18 and 0.27 SD higher in measures of social competence and emotional maturity (social-emotional skills).