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Immune checkpoint therapy responders display early clonal expansion of tumor infiltrating lymphocytes

Immune checkpoint therapy (ICT) causes durable tumour responses in a subgroup of patients, but it is not well known how T cell receptor beta (TCRβ) r…

Functional characterization of the MED12 p.Arg1138Trp variant in females: implications for neural development and disease mechanism

Seven female individuals with multiple congenital anomalies, developmental delay and/or intellectual disability have been found to have a genetic var…

Living next door to McDonald’s: a qualitative study of community submissions and resident realities pre- and post development

The proliferation of fast-food outlets in residential areas has raised growing concerns about their impact on community health, safety, and wellbeing…

Barriers and enablers to promoting grandchildren’s physical activity and reducing screen time: a qualitative study with Australian grandparents

With an increasing number of grandparents providing care to their grandchildren, calls have been made for these caregivers to be considered important…

Barriers and facilitators to mental health treatment access and engagement for LGBTQA+ people with psychosis: a scoping review protocol

The prevalence of psychosis has been shown to be disproportionately high amongst sexual and gender minority individuals. However, there is currently…

Mapping facility-based tuberculosis preventive treatment provision in Ethiopia: a geospatial analysis

Tuberculosis (TB) remains a major public health challenge in Ethiopia, despite being a preventable disease. TB preventive treatment (TPT) is a critic…

Respiratory infection- and asthma-prone, low vaccine responder children demonstrate distinct mononuclear cell DNA methylation pathways

nfants with frequent viral and bacterial respiratory infections exhibit compromised immunity to routine immunizations. They are also more likely to d…

CLEAR study

Do you have type 1 diabetes (T1D)? Do you sometimes struggle to recognise symptoms of low blood sugar

OPAL 2 study - with the Omnipod 5

– 24 years, who have been living with type 1 diabetes (T1D) for more than 12 months and are currently

Participant and caregiver perspectives on health feedback from a healthy lifestyle check

The usual output following health consultations from paediatric services is a clinical letter to the referring professional or primary care provider,…