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Showing results for "Neuromuscular disorders "
Helping families to unlock the mental and physical health benefits of connecting with nature and community through outdoor play - easily, and locally.
Community Involvement and Consumer Representatives are a really important part of our research. Find out what they have been working on.
ORIGINS has a large number of sub-projects exploring the link between a mother's diet during pregnancy and health outcomes of the child. Projects also explore nutrition and eating habits during the early years as well as general gut health
As well as ORIGINS long-term core research, there are a number of clinical trials, early interventions and shorter-term research studies that sit within ORIGINS. Known as sub-projects, these studies look at multiple aspects of child and family health and development.
Positive mental health, flourishing, and resilience to stress are not only critical to the overall wellbeing of a person but also their physical health, affecting both chronic and acute health conditions
Glioblastoma, a lethal high-grade glioma, has not seen improvements in clinical outcomes in nearly 30 years. Ion channels are increasingly associated with tumorigenesis, and there are hundreds of brain-penetrant drugs that inhibit ion channels, representing an untapped therapeutic resource. The aim of this exploratory drug study was to screen an ion channel drug library against patient-derived glioblastoma cells to identify new treatments for brain cancer.
High-grade glioma (HGG) cells reactivate neurodevelopmental programs regulated by ion channels to drive tumor progression. The activity of voltage-gated sodium channels (VGSCs) is fundamental to development, a target of blood-brain barrier (BBB)-permeable FDA-approved drugs, and aids tumor advancement in several cancers. However, the contribution of VGSC activity to HGG pathology remains unknown.
This study investigated the effects of Mindful Self-Compassion (MSC) training on the mental health of gender and sexually diverse young adults (aged 18–25 years) in Australia. A single-blind randomized controlled trial was conducted in 2020–2022 comparing an online-delivered 8-week group MSC training program with a waitlist control.
To determine the proportion of child maltreatment-related emergency department presentations in WA and describe the types of injuries associated with them.
The maternal experience of stressful events during pregnancy has been associated with a number of adverse consequences for behavioral development offspring...