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Research
Fetal androgen exposure and pragmatic language ability of girls in middle childhoodPrenatal exposure to testosterone has been shown to affect fetal brain maturation as well as postnatal cognition and behavior in animal studies.
Research
Paediatric Medicinal Formulation Development: Utilising Human Taste Panels and Incorporating Their Data into Machine Learning TrainingThis review paper explores the role of human taste panels and artificial neural networks (ANNs) in taste-masking paediatric drug formulations. Given the ethical, practical, and regulatory challenges of employing children, young adults (18-40) can serve as suitable substitutes due to the similarity in their taste sensitivity. Taste panellists need not be experts in sensory evaluation so long as a reference product is used during evaluation; however, they should be screened for bitterness taste detection thresholds.
Research
Taste-Masked Flucloxacillin Powder Part 1: Optimisation of Fabrication Process Using a Mixture Design ApproachIt is extremely challenging to formulate age-appropriate flucloxacillin medicines for young children, because flucloxacillin sodium (FS) has a lingering, highly bitter taste, dissolves quickly in saliva, and requires multiple daily dosing at relatively large doses for treating skin infections. In this paper, we describe a promising taste-masked flucloxacillin ternary microparticle (FTM) formulation comprising FS, Eudragit EPO (EE), and palmitic acid.
News & Events
Hopscotch 7th April 2022: The next generation of cancer treatmentsOur first Hopscotch event of 2022 explored exciting new frontiers of cancer treatments happening in the WA Kids Cancer Centre.
News & Events
Vaccination seminar presentationsOn Monday May 30, The Kids Research Institute Australia held a free public seminar on vaccination, hearing from paediatricians and infectious disease researchers.
News & Events
Fresh Science to target painful ear infectionsThe Kids's Dr Ruth Thornton is one of 12 finalists in the annual national Fresh Science competition with her research into middle-ear infections.
News & Events
Immunisation advice before, during and after pregnancyAre you pregnant or planning to have a baby? There are important vaccinations that you should consider to protect your health and the health of your baby.
News & Events
Community Research ExpoYou are invited to come and hear about our research, meet our researchers and express your interest in working together on current and future projects.
Research
Longitudinal analysis of respiratory outcomes among bauxite exposed workers in western AustraliaThis study investigated any associations between cumulative bauxite exposure and respiratory symptoms.