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Research
The overlapping burden of the three leading causes of disability and death in sub-Saharan African childrenDespite substantial declines since 2000, lower respiratory infections (LRIs), diarrhoeal diseases, and malaria remain among the leading causes of nonfatal and fatal disease burden for children under 5 years of age (under 5), primarily in sub-Saharan Africa.
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Systematic analysis of transcription start sites in avian developmentCAGE in combination with single-molecule sequencing technology allows mapping of TSSs and genome-wide capture of promoter activities state cell populations.
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Prenatal and perinatal risks for late language emergence in a population-level sample of twins at age 2This study investigated the extent to which prenatal and perinatal risk factors were associated with LLE in a population-level sample of twins at age 2 without overt disability.
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Premedication with salbutamol prior to surgery does not decrease the risk of perioperative respiratory adverse events in school-aged childrenPremedication with salbutamol to children prior to their surgery did not reduce their risk of Perioperative respiratory adverse events
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Bipolar disorder in children and adolescents: diagnostic inpatient rates from 2000 to 2013 in GermanyThe rate of Bipolar Disorder as a discharge diagnosis in German minors has increased significantly, consistently exceeding the general trend for a rise in rates for mental disorders
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Molecular actions of Vitamin D in reproductive cell biologyThe aim of this work is to review current metabolic and molecular aspects of the VitD-VitD receptor axis in reproductive medicine
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Coffee and tea consumption during pregnancy and risk of childhood acute myeloid leukemia: A Childhood Leukemia International Consortium (CLIC) studyWe investigated the potential association of maternal coffee and tea consumption during pregnancy with childhood acute myeloid leukemia risk
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A population health approach in education to support children's early development: A Critical Interpretive SynthesisThe results from this review indicate that it would indeed be plausible to adapt the population health approach to sites and schools
News & Events
Further evidence of testosterone link to autismA new study from Perth's The Kids for Child Health Research has uncovered more evidence of a link between early testosterone levels and autism.
Research
Interleukin-4 modulates type I interferon to augment antitumor immunityDespite advances in immunotherapy, metastatic melanoma remains a considerable therapeutic challenge due to the complexity of the tumor microenvironment. Intratumoral type I interferon (IFN-I) has long been associated with improved clinical outcomes. However, several IFN-I subtypes can also paradoxically promote tumor growth in some contexts.