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Research

Severity Assessment in CDKL5 Deficiency Disorder

A severity assessment was rapidly developed with input from multiple stakeholders. Refinement through ongoing validation is required for future clinical trials.

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An urgent need for antimicrobial stewardship in Indigenous rural and remote primary health care

We write this perspective to raise awareness of antimicrobial resistance as an issue in Indigenous primary health care

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Comparing adolescent and parent reports of externalizing problems: A longitudinal population-based study

Substance use, depression and low school motivation impacted on discrepancy in externalizing behaviour scores for 14-year-old male adolescents and their parents

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High-Rise Apartments and Urban Mental Health—Historical and Contemporary Views

High-rise apartment buildings have long been associated with the poor mental health of their residents

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Antisense Transcription in Loci Associated to Hereditary Neurodegenerative Diseases

Evidence for the existence of additional regulatory mechanisms of the expression of neurodegenerative disease-causing genes by antisense long noncoding RNAs

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Validation of an Asbestos Job-Exposure Matrix (AsbJEM) in Australia: Exposure-Response Relationships for Malignant Mesothelioma

Accuracy of the AsbJEM in determining exposure-response relationships between asbestos exposure estimates and malignant mesothelioma incidence

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Epigenetic Age Acceleration in Adolescence Associates with BMI, Inflammation, and Risk Score for Middle Age Cardiovascular Disease

Accelerated epigenetic age in adolescence was associated with inflammation, BMI measured 5 years later, and probability of middle age cardiovascular disease

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Lessons learned in genetic research with Indigenous Australian participants

We reflect on the lessons learned from a recent genome‐wide association study of rheumatic heart disease with Aboriginal Australian participants

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Oestrogen amplifies pre-existing atopy-associated Th2 bias in an experimental asthma model

The role of oestrogen in experimental atopic asthma, and guide future research on sex-related variations in atopic asthma susceptibility/intensity

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Simultaneous Targeting of DNA Replication and Homologous Recombination in Glioblastoma with a Polyether Ionophore

Our findings highlight the potential of salinomycin to induce DNA lesions and inhibit homologous recombination to greatly enhance the effect of radiotherapy