The airway mucosal epithelium is the main gateway of entry for numerous human respiratory viruses, including human influenza virus, respiratory syncy…
To provide updated evidence-based clinical guidance in the management of infants with bronchiolitis presenting to emergency departments (EDs), genera…
Respiratory disease is a leading cause of hospitalisations in children with cerebral palsy (CP). Over 40% of individuals with CP are born preterm; ho…
Functional studies of how early-life interventions shape the airway microbiome remain scarce. Here, we performed metagenomic sequencing of 704 longit…
People born preterm (<37 weeks’ gestation) have lower peak oxygen consumption (peak VO2), a well-established indicator of long-term health outcomes,…
Preterm birth is associated with lifelong respiratory sequelae, yet our understanding of lung function trajectories across the lifespan remains limit…
Obesity is linked to altered lung function and increased perioperative respiratory adverse events (PRAEs). We examined the effects of obesity, respir…
Pulmonary exacerbations pose a significant clinical burden on people with cystic fibrosis (pwCF). Whether management of exacerbations should change i…
Since the first description of bronchopulmonary dysplasia (BPD), multiple definitions to diagnose BPD and its grading have been published. Several st…
The airway epithelium is the primary structural and functional airway barrier and orchestrates innate immunity. Some children may have underlying epi…