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Showing results for "lung disease preterm"
Bushfires can have a considerable impact on our health, with some symptoms lasting long after the flames are extinguished. And our children are amongst the most vulnerable.
Scabies causes considerable morbidity and leads to severe bacterial infection and immune-mediated disease
Prospective birth cohort studies tracking asthma initiation and consolidation in community cohorts have identified viral infections occurring against a...
The aim of this study was to explore associations between severe respiratory infections and atopy in early childhood with persisting wheeze and asthma.
Elucidation of early life factors is critical to understand the development of allergic diseases, especially those manifesting in early life such as food allerg
Poor maternal diet during pregnancy is a risk factor for severe lower respiratory infections in the offspring, but the underlying mechanisms remain elusive. Here, we demonstrate that in mice a maternal low-fiber diet led to enhanced LRI severity in infants because of delayed plasmacytoid dendritic cell recruitment and perturbation of regulatory T cell expansion in the lungs.
Although debate surrounding the mechanism or mechanisms governing this causal pathway remains intense, demonstration of the capacity of pretreatment...
No reproducible associations with KIR2DL4 genotype were identified, leading us to conclude that the KIR2DL4 9A/10A polymorphism has no influence...
These findings suggest that this modified version of SLIT should be considered for retesting of mucosal-based immunotherapy for atopic asthma prevention.
Previous genome-wide association studies revealed multiple common variants involved in eczema but the role of rare variants remains to be elucidated. Here, we investigate the role of rare variants in eczema susceptibility. We meta-analyze 21 study populations including 20,016 eczema cases and 380,433 controls. Rare variants are imputed with high accuracy using large population-based reference panels.