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Research
Overall efficacy of HPV-16/18 AS04-adjuvanted vaccine against grade 3 or greater cervical intraepithelial neoplasiaWe report vaccine efficacy against CIN3+ and adenocarcinoma in situ (AIS) in the end-of-study analysis of PApilloma TRIal against Cancer In young Adults.
Research
Efficacy, safety, and immunogenicity of the human papillomavirus 16/18 AS04-adjuvanted vaccine in women older than 25 yearsIn women older than 25 years, the HPV 16/18 vaccine continues to protect against infections, cytological abnormalities, and lesions associated with HPV 16/18
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How Does Support From Peers Compare With Support From Adults as Students Transition to Secondary School?Students who expect and experience a positive transition to secondary school are generally well-supported by their peers, school, and family.
Research
Genetic variants in ER cofactor genes and endometrial cancer riskGiven that the transcriptional regulatory activity of estrogen receptor (ER) is modulated by its biochemical cofactors, genetic variation within the ER...
Research
Evening and night work schedules and children's social and emotional well-beingThe findings show that both mothers’ and fathers’ evening and night work schedules are linked to an increase in children's externalizing and internalizing behavior
News & Events
The PERSIST StudyThe Persist Study Community Workshop. Help us to understand how to engage other youth who live with T1D!
News & Events
Flu Program for PatientsFlu season is here. The Paediatric Influenza Vaccine Program has started at PCH. Available now to inpatients and children attending outpatient appointments, everyone is encouraged to get the influenza vaccination.ne.
Research
Investigation of structural brain correlates of neurological soft signs in individuals at ultra-high risk for psychosisIncreased severity of neurological soft signs (NSS) in schizophrenia have been associated with abnormal brain morphology in cerebello-thalamo-cortical structures, but it is unclear whether similar structures underlie NSS prior to the onset of psychosis. The present study investigated the relationship between severity of NSS and grey matter volume in individuals at ultra-high risk for psychosis stratified for later conversion to psychosis.
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Reduced heart rate variability in remitted bipolar disorder and recurrent depressionHeart Rate Variability was found to be lower in the bipolar and depression groups, compared with control subjects
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The Effect of Hypoglycemia on Spectral Moments in EEG Epochs of Different Durations in Type 1 Diabetes PatientsThe potential of using an electroencephalogram (EEG) to detect hypoglycemia in patients with type 1 diabetes has been investigated in both time and frequency domains. Under hyperinsulinemic hypoglycemic clamp conditions, we have shown that the brain's response to hypoglycemic episodes could be described by the centroid frequency and spectral gyration radius evaluated from spectral moments of EEG signals.