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Comparison of experiences in two birth cohorts comprising young families with children under four years during the initial Covid-19 lockdown in Australia and the UK: A qualitative studyThis study aims to understand the experience and impact of the initial COVID-19 lock-down in young families with children aged below 4 years. Free text questions were administered to participants in the ORIGINS (Australia) and Born in Bradford (UK) cohort studies to collect qualitative information on worries, concerns and enjoyable experiences during the pandemic.
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Probiotic peanut oral immunotherapy versus oral immunotherapy and placebo in children with peanut allergy in Australia (PPOIT-003): a multicentre, randomised, phase 2b trialOral immunotherapy is effective at inducing desensitisation to allergens and induces sustained unresponsiveness (ie, clinical remission) in a subset of patients, but causes frequent reactions. We aimed to investigate whether addition of a probiotic adjuvant improved the efficacy or safety of peanut oral immunotherapy.
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Validation of monoclonal anti-PKC isozyme antibodies for flow cytometry analyses in human T cell subsets and expression in cord blood T cellsWe have undertaken to validating the specificity of commercially available antibodies marketed for flow cytometry to measure PKCα, βI, βII, δ, ε, η, θ, ζ, ι/λ and μ
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Each meal matters in the exposome: Biological and community considerations in fast-food-socioeconomic associationsAs we discuss, equal weekly visits to major fast-food outlets by the affluent and deprived do not translate into biological equivalency.
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Bugging allergy; role of pre-, pro- and synbiotics in allergy preventionHere, we summarize and discuss findings of randomized clinical trials that have examined the effects of these strategies on short and long-term.
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In-utero exposures and the evolving epidemiology of paediatric allergyThis paper discusses the rising prevalence of allergic disease in children. This review article considers recent findings in the field of paediatric immune...
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Circulating Epithelial Cell Cytokines Are Associated With Early-Onset Atopic DermatitisDebbie Susan Palmer Prescott BSc BND PhD MBBS BMedSci PhD FRACP Head, Nutrition in Early Life Honorary Research Fellow debbie.palmer@uwa.edu.au
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A Family's Journey at JHC: Analyses of routinely collected dataDesiree Silva MBBS, FRACP, MPH, PhD Co-Head, ORIGINS Co-Head, The ORIGINS Project Professor Desiree Silva is Co-Director of ORIGINS and a Professor
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ADAPTS: Antibiotic Dysbiosis And Probiotics Trial in infantSDesiree Peter Silva Richmond MBBS, FRACP, MPH, PhD MBBS MRCP(UK) FRACP Co-Head, ORIGINS Head, Vaccine Trials Group Co-Head, The ORIGINS Project Head
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Environmental and lifestyle changes in the antenatal population over the past three decades: A comparative study utilising Raine Study and Joondalup Health Campus birth cohort dataInvestigators: Catherine Nguyen, Lauren Fisher, Lauren Nguyen This study investigated changes in prevalence of environmental and lifestyle risk