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Streptococcus pyogenes Surveillance Through Surface Swab Samples to Track the Emergence of Streptococcal Toxic Shock Syndrome in Rural Japan

Japan recently experienced a record surge in streptococcal toxic shock syndrome. Our environmental surveillance study reveals that Streptococcus pyogenes persists seasonally, peaking in autumn and winter in rural Japan. The dominant emm1 M1UK sublineage and csrS mutations heighten virulence, highlighting the urgent need for targeted surveillance and interventions.

Lentiviral vector gene therapy and CFTR modulators show comparable effectiveness in cystic fibrosis rat airway models

Mutation-agnostic treatments such as airway gene therapy have the potential to treat any individual with cystic fibrosis (CF), irrespective of their CF transmembrane conductance regulator (CFTR) gene variants. The aim of this study was to employ two CF rat models, Phe508del and CFTR knockout to assess the comparative effectiveness of CFTR modulators and lentiviral vector-mediated gene therapy. 

The AREST CF experience in biobanking - More than just tissues, tubes and time.

Research to further improve outcomes for people with CF is dependent upon well characterised, archived and accessible clinical specimens.

In “high-risk” infants with sufficient vitamin d status at birth, infant vitamin D supplementation had no effect on allergy outcomes: A randomized controlled trial

Early infancy oral vitamin D supplementation does not appear to reduce the development of early childhood allergic disease

Crowding and other strong predictors of upper respiratory tract carriage of otitis media-related

We investigated predictors of nasopharyngeal carriage in Australian Aboriginal and non-Aboriginal children.

Find out more about our brand new Showcase Projects

Our showcase projects are a demonstration of how we at The Kids Research Institute Australia are committed to a new way of working.

Telethon Institute research provides new insights into the cause of asthma attacks

Telethon Institute for Child Health Research scientist Dr Anthony Bosco has been recognised for his cutting edge research investigating asthma attacks

Impact: Research Translation

On this Research Impact page, learn about our work that's actively translated as Government policy or in active practice. Learn how our research is making a difference in people's lives - not tomorrow, next week, or next year - but today!

Speakers

Meet the speakers Prof. Bob Hancock Title: Canada Research Chair in Health and Genomics; Director, Centre for Microbial Diseases and Immunity

Not just a cough: Wet cough research prompts significant change in clinical and community practice

Results from a world first-study measuring prevalence of chronic wet cough and protracted bacterial bronchitis in four Kimberley Aboriginal communities have highlighted the enormity of the health problem.