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PI3K activation in neural stem cells drives tumorigenesis which can be ameliorated by targeting the cAMP response element binding proteinA novel mouse model for glioma demonstrating that the PI3K pathway is important for initiation of tumorigenesis
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Maternal high fat diet compromises survival and modulates lung development of offspring, and impairs lung function of damsWhile maternal high fat diet compromised litter survival, it also promoted somatic and lung growth (increased lung volume) in the offspring
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Planetary Health: From the Wellspring of Holistic Medicine to Personal and Public Health ImperativeHere, we explore the history of planetary health and describe its relevance to contemporary healthcare
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ERS technical standard on bronchial challenge testing: pathophysiology and methodology of indirect airway challenge testingAssessment of airway hyperresponsiveness are valuable tools to understand and to monitor airway function and to characterise the underlying asthma phenotype to guide therapy
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Beyond the reactive-proactive dichotomy: Rage, revenge, reward, and recreational aggression predict early high school bully and bully/victim statusWe discuss the implications of addressing Revenge and Recreation, as well as Reward and Rage aggression motives, for bullying prevention and intervention strategies
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Interleukin-1 is associated with inflammation and structural lung disease in young children with cystic fibrosisOur data associates IL-1α with early structural lung damage in CF and suggests this pathway as a novel anti-inflammatory target
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Research priority setting in childhood chronic disease: a systematic reviewResearch priority setting activities in paediatric chronic disease cover many discipline areas and have elicited a broad range of topics
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Socioeconomic status and early child development in East Asia and the Pacific: The protective role of parental engagement in learning activitiesResults indicated the existence of SES gradients in early development in multiple domains in China, Mongolia, Papua New Guinea, Timor-Leste, and Vanuatu
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A group randomized controlled trial evaluating parent involvement in whole-school actions to reduce bullyingWhole-school capacity-building intervention in early and middle childhood can improve the likelihood and frequency of positive parent–child communication about bullying
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Childhood Maltreatment and Early Developmental Vulnerabilities at Age 5 YearsThis study examined associations between maltreatment and early developmental vulnerabilities in a population sample of 68,459 children