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Dornase alfa as an adjunct therapy to treat chronic ear infections

Chris Glenn Lea-Ann Peter Ruth Brennan-Jones Pearson Kirkham Richmond Thornton PhD BA (Education) PhD Candidate PhD MBBS MRCP(UK) FRACP PhD Head, Ear

Understanding Engagement in Digital Mental Health and Well-being Programs for Women in the Perinatal Period: Systematic Review Without Meta-analysis

Pregnancy and the postnatal period can be a time of increased psychological distress, which can be detrimental to both the mother and the developing child. Digital interventions are cost-effective and accessible tools to support positive mental health in women during the perinatal period.

Devising a Missing Data Rule for a Quality of Life Questionnaire - A Simulation Study

The aim of this study was to devise an evidence-based missing data rule for the Quality of Life Inventory-Disability (QI-Disability) questionnaire specifying how many missing items are permissible for domain and total scores to be calculated using simple imputation.

Conventional Therapies Deplete Brain-Infiltrating Adaptive Immune Cells in a Mouse Model of Group 3 Medulloblastoma Implicating Myeloid Cells as Favorable Immunotherapy Targets

Medulloblastoma is the most common childhood brain cancer. Mainstay treatments of radiation and chemotherapy have not changed in decades and new treatment approaches are crucial for the improvement of clinical outcomes. To date, immunotherapies for medulloblastoma have been unsuccessful, and studies investigating the immune microenvironment of the disease and the impact of current therapies are limited.

Time investment and child development

This project aims to explore how Australian children spend their time over an extended and important period of their lives (from birth to 16/17 years old) and how such time allocation contributes to their development outcomes.

The role of virus defence in childhood asthma

The overarching aim of this project is to understand how plasmacytoid dendritic cells function in children with asthma and how genes and environmental stimuli influence these cells.

Infant study shines new light on eczema prevention

A study led by The Kids Research Institute Australia has suggested vitamin D supplementation in babies is no match for sunlight when it comes to preventing eczema.

‘Invisible’ children of imprisoned parents at risk of falling through the cracks

A study by The Kids has found children with a parent who has gone to prison are significantly more likely to have poor development outcomes.

Trans young people at high risk of depression and suicide

Trans Pathways is the largest ever survey conducted into the mental health of trans young people in Australia.

Am I a good enough parent?

I spend a lot of time listening to parents and a lot of time analysing what they are thinking, how they are coping, how they behave and what they are doing.