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Gut microbiome and innate immune response patterns in IgE-associated eczemaGut microbiome patterns have been associated with predisposition to eczema potentially through modulation of innate immune signalling.
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Maternal fish oil supplementation in pregnancy: a 12 year follow-up of a randomised controlled trial.We aimed to investigate the long-term effects (12 years) of fish oil supplementation in pregnancy on neurodevelopment, including cognition, language and fine...
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The maturation of immune functions in pregnancy and early childhoodThis book chapter explains the maturation of immune functions during pregnancy & in early childhood, and addresses the importance of early environmental...
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Developing primary intervention strategies to prevent allergic diseaseAllergic diseases are a major cause of morbidity in the developed world, now affecting up to 40 % of the population with no evidence that this is abating.
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Effects of maternal n-3 fatty acid supplementation on placental cytokines, pro-resolving lipid mediators and their precursorsThe aim of this study was to determine whether supplementation with fish oil-derived n-3 PUFA during pregnancy modifies modifies placental PUFA composition...
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In utero and postnatal vitamin D exposure and allergy riskThis review article examines the evidence of the impact of in utero and postnatal vitamin D exposure on allergy risk in childhood
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The role of family and maternal factors in childhood obesityThe aim of this study was to investigate the relationship between a child's weight and a broad range of family and maternal factors.
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A Family's Journey at JHC: Analyses of routinely collected dataDesiree Silva MBBS, FRACP, MPH, PhD Co-Director, ORIGINS desiree.silva@thekids.org.au Co-Head, The ORIGINS Project Professor Desiree Silva is
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ADAPTS: Antibiotic Dysbiosis And Probiotics Trial in infantSDesiree Peter Silva Richmond MBBS, FRACP, MPH, PhD MBBS MRCP(UK) FRACP Co-Director, ORIGINS Head, Vaccine Trials Group desiree.silva@thekids.org.au
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Environmental and lifestyle changes in the antenatal population over the past three decades: A comparative study utilising Raine Study and Joondalup Health Campus birth cohort dataInvestigators: Catherine Nguyen, Lauren Fisher, Lauren Nguyen This study investigated changes in prevalence of environmental and lifestyle risk